Exploring these configurations and using them in your melodic lines - both improvised and composed - can help take one "out of the ordinary path", to quote John Coltrane, as he referred to his own then revolutionary use of the Descending Major 3rds Cycle (aka "Coltrane Changes"), which gave birth to a number of his challenging compositions, the best known being "Giant Steps".
Using "Giant Steps" chord changes, I composed a one-chorus (16-bar) etude, featuring the aforementioned trichord as a basis for the solo melodic line.